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糖果派对2怎么玩9662ab澳亚国际的

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2017-05-25 11:05 ????:????ҽ ?Ķ?:

盛大娱乐官网合乐888手机网页版

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2.??΢???? ??ͷ????????????棺????Ƥ??????Ϊ1?л?ɫľ˨??ϸ????????Ϊ8-9?б?????ϸ?????ڻ?ɫ??ľ˨??????????ʯϸ??ɢ?ڣ???Ƥ??ϸ????С????Ƥ??ռ?󲿷֣?ϸ???к?????????ɢ??С??ɸ??Ⱥ??ż??1??????????ά???????γɲ㻷?Գ??????߽??Ρ?ľ?ʲ??ܳ?λ???γɲ??????ڲ࣬?????Գ?“V”?λ????״???У?ľ??????֯?Ϸ???貿????ϸ????????????

3.??ĩ???????һư?ɫ???ٵ????????࣬?????????λ?Բ????Σ???????Բ?Σ?ֱ??2-20μm?????ʵ?״??ʮ??״??????״????????2-7??????ิ?϶??ɡ??ں???Ƥ????Ƭ?ټ???????۳ʶ???Σ????ܱڲ??????????еij???״ͻ??ϸ??ǻ????ǻ?ں???ɫ???ʯϸ???ټ???ɢ?ڣ?ֱ??Լ53-125μm???ƿ????ԡ??ܾ?Ե?ƿ׼????Ƶ???ֱ??20-48μm???Ƹ?Ƭ??Ϊ?????????????ı?????֯??Ƭ??

????ѧ?ɷ֡????Ӻ???ͷ?aconitine????????ͷ?mesaconitine????????ͷ?hypaconitine??????????ͷ????talatisamine???????ڰ???higeramine??????????ȥ?׻???????ҩ?demethylcoclaurine???????Ƽ??Ȼ??coryneine chloride???????????
????? ??ȫ???в?ҩ??ࡷ??????? ??ҩ?????ơ?????? ??ƴ????F??i Yn C??o ????????è?ۻ??????ӻ????󻨷???ݡ???צ??????????[????] ????Դ??ëݢ?ƴ?ȸ...?鿴?????????
?isodelphinine??????????????ͷ?benzoyl mesaconitine???????????neoline???????????fuziline????????ͷ?beiwutine?????????ͷ?karakoline????ȥ????ͷ?deoxyaconitine????????ͤ?fuzitine????׼?????ͷ?songorine??????ण?uracil??????????ͷ?jiangyouaconitine?????½?????ͷ?neojiangyouaconitine????ȥ????ë?˼salsolinol???ȡ?

??ҩ?????á?1.???????úͶ??ڷ??ڵ?Ӱ?죺????ڷ?????20%???2.5ml??100g??50%???2ml??100g?Լ?ȩ????????Ĵ????׹ؽ??׾??зdz????ŵ????????ã?P??0.01?????츽Ƭ???0.5g??kg???ܷdz????ŵ????ƴ??????????ס??????ӵļ״???ȡ???????Ƶ????????С??ǻѪ????͸?????ӺͽDz?˽???????׹ؽ??ס?????ڷ?300mg??kg???׹ؽڵ??????Թؽ??׵????ñȿڷ?50mg??kg??̫??ǿ???ڷ?30mg??kgʱ??????????ѿ?׵????????ñȿڷ?20mg??kg?ɵ???ǿ??????ˮ?崼??Һ??ÿ1ml=??ҩ2g????ǻע?䲻ͬ???????ڴ??󣬶Ե????Թؽ????;??в?ͬ?????????ã???ǿ????ҩ?????????????ԡ??Ը??ӿ??????õĻ??ƿ?????һ?????б????????Ӻ?????????ά????C?͵??޴????????٣?????й17-ͪͬ??̴????ӣ?Ѫ???????԰?Ѫ????٣???????????ø?͸????????ӣ??????˷ܴ???-??????Ƥ??ϵͳ?????á????б????????г??????ٺ󣬸??ӵĿ????????Ա??棬??Ϊ?俹???????봹??-??????Ƥ??ϵͳ?޹ء???????Ϊ???ӱ?????????Ƥ?ʼ????????á?

2.??ʹ???򾲺Ͷ????µ?Ӱ?죺????0.1-1g??kg???ڶ????????ѹ?ȴ???β?????????ʹ?͸?ǻע??????????С??Ť?巴Ӧ??????ˮ?崼??Һ??1ml??2g??ҩ????ǻע?????С?󣬿????С???ʹ??ֵ??С??ڷ??????????Һ???ӳ??????ͱ????Ƶ?˯??ʱ?䣬?????????˶??????ܽ??????´?2Сʱ֮?ã??????Ƹ???????ͬ?????????????????á????ں???????£????????Һ??ˮ??????????ƺ???????ļ??ʹ?????????½???????ʹ???͵????»ָ????ӳ?????ʱ?䣬?????????ʡ?????ˮ???20g??kg??θ????С?󣬿ɷdz??????ӳ??ܺ?С??Ĵ???ʣ?P??0.01????????ˮ????????ŶԿ?С??ˮ??Ӧ???ʹ????????????????񣻻??????ŶԿ????? ???? ??ҩ?????ơ????? ??ƴ????B M ????????????? ????Դ????ƷΪ??꪿?ֲ?? ???? Ricinus communis L.?? ???? ???????????ӡ????? ?? ?? Ҷ ??ҩ??????ɸ?...?鿴?????????ͺ???кҶ ??кҶ ???й?ҩ?䡷????кҶ ??ҩ?????ơ???кҶ ??ƴ????F??n Xi Y ??Ӣ??????FOLIUM SENNAE ????????кҶ ????Դ????ƷΪ????ֲ?? ??Ҷ??к Cassia angustif...?鿴??кҶ?????????С??ҩ???Ը?к?????Ȱ巨???е???ʹ???õȣ?????Ϊ?Ǹ???????ֹʹ??ҩ??ѧ??????

3.????Ѫ??ϵͳ?????ã???

3.1.ǿ?ĺ???ѹ???ã?ȥ????ҩ???Ǹ????е?ǿ?ijɷ?֮һ????????΢????????Ѫ??ϵͳ?????ú?ǿ???????????????????ģ???λ???ĺ?????˥????????ļ???????????????Ȯ????ע??l-2μg/kg????????ѹ????????????ʺ?????????????ӣ????????Ժ????ܶ????Լ?ȫ??Ѫ?????????ͣ??ļ??????????ӣ??????????ļ?ϸ??????Ƶ?ʺͷ???Ҳ???ӡ????????ÿɱ??ĵð???ϣ???Щ??????????????ص????????ơ??????е?ȥ????ë?˼???һ????β-?˷ܼ????????˷??????????ķ?????????????Ƶ?ʣ?????ע?????????????ͻټ??????Ѫѹ???ӿ????ʣ????ټ???????ȥ????ë?˼????ѹ???ñ?????????????У??????Ϊȥ????ë?˼???ж?β-???弰α-????????˷????á??????й??Ƽ???????Ե???ѹ??ǿ?????ã?????ע??40μg/kg??ʹ????Ѫѹ????50%??3×10(-6)g??ml??ʹ???????????ķ??????????Ⱥ?Ƶ?ʷֱ?????250??120%???Իټ???èҲ?????????á???????ѹ???ÿ???α-?????????????????ͼ?-????????ȡ????????ѹ???ü??????????ķ???????Ҳ?ܱ??񾭽????ҩ-???????????Կ????????????????˷??񾭽ڻ??ǰ??ά?йء?

3.2.?????ʺ?????ʧ????Ӱ?죺ȥ????ҩ???ܼ??????ʣ???ʵ???Ի?????????ʧ???и??????á??ٴ??۲?Ҳ֤ʵ??ȥ????ҩ??Ի?????????ʧ???????Ե????????á?????ע??󣬲??˵????ʾ??в?ͬ?̶ȵ????ӣ?????Ķ??????ָ???????ˮƽ??񼷿???ͺͽ??????Ҵ??????ܵõ????ƣ??Ӷ?ʹ???????ͼ??????ʧ?????????ҪΪ????A-H???ڡ?ʵ?黹??????ȥ????ҩ?????????????ض?β-????????????????׺??????ƣ??????ڻ???????С????????????ء??Ӷ?ֱ??֤??ȥ????ҩ????β-?????????????岿?ּ?????????????β2-????Ҳ?????Եļ??????ã??????ñ?ֱ?Ӽ????ļ?B1-????ǿ??Ϊ???͸??ӵĻ????????ṩ?˲???֤?ݡ?

???ӵ?ˮ?ܲ??֣???????ͷ??????????ˮ?ܲ??֣?60??120mg??kg???൱??С????ע??LD50??1??10-1??5??????????ˮ?????գ?????ע????ڴ??󣬸?ҩ5???Ӻ???ע????ͷ??30μg/kg????¼????????ʧ??ʱ????ȶ??????????ӳ٣?P??0.001??????120mg??kg???6ֻ????20?????ھ?δ????????ʧ????P??0.001????????ڷ?????ˮ?ܲ???550??1100mg??kg???Կ???ͷ?????µ?????ʧ?????ã???õ????????ƵĽ???????ӵ?ˮ?ܲ??ֶԾ???ע????ͷ??40μg/kg??20μg/kg?Ĵ??󣬳???????ʧ??5???Ӻ󣬷ֱ???ע??200mg??400mg??kg??ʮ??ָ??????500mg??1000mg??kg??????ʮ?????ŵ?תΪ???????ɣ?P??0.001??????????ˮ?ܲ??ֶ??۰??򡢻??ȷ????µ?????ʧ????Ч?????????????ͬһ??ҩ??ͬʱ????????ͶԿ?????ʧ???Ļ?ѧ?ɷ֡?

3.3.???ݿ˵?Ӱ?죺????ˮ?ܲ???2mg????kg.min????1??30mg??kg??????ע???????ڶ????????ݿ˵?è??????????ԶԿ???????ѹ????BP??????????????ѹ????LVP??????????ѹ????????????ʣ?LVdp??dt??max???Ľ??ͺ????ʺͼ??????ӳ?????ʱ?䡣???????ڶ?????????ݿ??????????á?????????ȡ??801?????????ӳ??????ݿ˴???Ĵ??ʱ?䡣

3.4.??Ѫ??????Ӱ?죺??????????????Ѫ?ܵ????ã????Ӽ????????????????Ȯ??è?ĺ?֫Ѫ?ܣ???ͷ???Ҳ?д????á?????ע?丽??ˮ?ܲ???7.5??15??30mg??kg????ʹ????Ȯ?ɶ???Ѫ?????ֱ?????30??70??129%??????????0.42??50%?????ÿ?ά??10???????ң??????ÿɽ????ø??Ӻ???֫??ů??ԭ??

3.5.???ļ?ȱѪ??Ӱ?죺????ע??Һ??ˮ?ܲ??ֶԼ????ļ?ȱѪ?????Եı??????á??????ӳ?С????ȱ??ʱ?䣬???ͼ???????ø???ԡ??Կ??????Ҷ??????Ĵ??????ļ?ȱѪ?????ż??ٽ???ǰ??֧?????????Ȯ????Ĥ??ͼST?ε?????Լ?ST?????ߵ???????

3.6.???????ã?????ˮ???????????ӳ?????????????Ѫøԭʱ?估??Ѫøԭ????ʱ?䡣????ǿ??ע??Һ??ÿ1ml??ȥ????ҩ??3mg??4ml??????5%??????ע??Һ400ml?У??ֱ???Ȯ???????Բ??ģ????ά?־?????Σ?ͬʱ?????ķ??ڵ????ⶨ񼷿??ָ?ʱ?䣨SNRTc????????Ĥ?𲫵??⡣??????ָ???ע??????ʼӿ죬SNRTc?????⣬??????𲫵?Ҳ?????ƶ???????????Ĵμ??𲫵???????񼷿??????Ϊ?ٴ????Ʋ???ṩ?????ݡ?????ˮ?????дٽ?ѪС??ۼ??????á???ͷ?????н???Ѫ?????á?

4.?????߹??ܵ?Ӱ?죺?۲츽??ע??Һ??С??Ѫ???ܾ?ø???ԡ?ѪҺ???弰Ƣ?࿹??ϸ???Ͷ?????Ѫ?岹?庬????Ӱ?죬???ֿ????С????Һ???߹??ܼ?????Ѫ?岹?庬????????С??Ѫ???ܾ?ø??????????Ӱ?죻??RE??????ϸ??ת??ʵ???о??Ի???ϸ??????Ӱ??ʱ???֣?????ע??Һ??ʹTϸ????RE?????γ?ϸ????????????0.4ml????kg.d????9?죨Ƥ??ע?䣩????ʹ???ܰ?ϸ??ת??????????????????ձȽ?P??0.01??

5.?????鶯??ģ?͵????û??ƣ??ø?ЧҺ??ɫ??-?绯ѧ??????ã??????Ի???Ϊ???Ӷ??Լ????ⶨ?ɵ???????????????????????Ե??????񾭵??ʡ??۲?????ҩ???ӵ?Ч??????????????ɵ????????????????ȥ?????????أ?NA?????????????½??????????أ?A?????ߣ?P????0.05)???ø??Ӻ??ָܻ????????ҿ?ʹ?ɵ???????????????????Ͱ???DA???????ߣ?P?ֱ?0.05??P??0.01)??3??4-???ǻ??????ᣨDOPAC???½???P??0.001)????ʹ????????5-??ɫ????5-HT?????ߣ?P??0.001)????ҩ?????鼰???????󶼱???ΪDA??DOPAC??5-HT??5-????????ᣨ5-HTAA????ֵ???ߣ?P??0.01-0.001)????ʾ?????????????????Ե???????ø???ԡ?

?????ԡ????ӣ?δ?ӹ???Ʒ??С??ڷ?LD50Ϊ5.49g??kg??????ע??Ϊ0.49g??kg???ӹ?????С??ڷ?LD50Ϊ16lg??kg??????ע??Ϊ2.8g??kg???츽Ƭ???С??ڷ??;???ע???LD50?ֱ?Ϊ17.42g??kg??3.516g??kg??????ˮ?崼??Һ1?θ?ǻע???С??LD50Ϊ26.30g??kg??ȥ????ҩ??С????ע??LD50Ϊ58.9mg??kg????ǻע??Ϊ300mg??kg???ڷ?Ϊ3.35g??kg??˫???ͺ͵?֬?????????????Ķ??Լ???5????ͷ?????Ҫ?????????ƺ?????????????ʧ??????????Ķ?????????ͨ???˷?????Ͷ??????ֱ????????????

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16.??ҽѧ??Դ????????????Ҫ???ƣ?ȥ?อ?????????????????㣬????Ƣθ??

17.??꽣????อ?????????????棬ʪ????ʹ??θ???׶????ξ??գ?????ɢ?ա?

18.???ùţ??ζ???Ϊ??????ǿ???ʡ?

19.?????ݸ?Ŀ???????????˺??????????ޣ??к??з磬̵?????ʣ???b??С??????????ʪ??ԣ???????????ͷ?磬????ͷʹ????к??????????Ƣй????ű???????ò?Ż?ܣ???θҭ????Ӹ?Ҳ???????©?䴯???ϴ??飬??????????

20.?????ݱ?Ҫ??????????????纮ʪ??

21.?????ݴ??¡????ζ????Ұף?һ?г???????֤֮??

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